Publications
“The joy of discovery is certainly the liveliest that the mind of man can ever feel”
- Claude Bernard -
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A microRNA signature that correlates with cognition and is a target against cognitive decline. Md Rezaul Islam, Lalit Kaurani, Tea Berulava, Urs Heilbronner, Monika Budde, Tonatiuh Pena Centeno, Vakthang Elerdashvili, Maria-Patapia Zafieriou, Eva Benito, Sinem M Sertel, Maria Goldberg, Fanny Senner, Janos L Kalman, Susanne Burkhardt, Anne Sophie Oepen, Mohammad Sadman Sakib, Cemil Kerimoglu, Oliver Wirths, Heike Bickeböller, Claudia Bartels, Frederic Brosseron, Katharina Buerger, Nicoleta-Carmen Cosma, Klaus Fliessbach, Michael T Heneka, Daniel Janowitz, Ingo Kilimann, Luca Kleinedam, Christoph Laske, Coraline D Metzger, Matthias H Munk, Robert Perneczky, Oliver Peters, Josef Priller, Boris S Rauchmann, Nina Roy, Anja Schneider, Annika Spottke, Eike J Spruth, Stefan Teipel, Maike Tscheuschler, Michael Wagner, Jens Wiltfang, Emrah Düzel, Frank Jessen, Delcode Study Group; Silvio O Rizzoli, Wolfram-Hubertus Zimmermann, Thomas G Schulze, Peter Falkai, Farahnaz Sananbenesi, Andre Fischer.
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Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues Mehani B, Narta K, Paul D, Raj A, Kumar D, Sharma A, Kaurani L, Nayak S, Dash D, Suri A, Sarkar C, Mukhopadhyay A. Scientific Reports (2020)
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A combined miRNA-piRNA signature to detect Alzheimer's disease Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, Synofzik M, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A, Fischer A. Translational Psychiatry (2019)
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Childhood Trauma in Schizophrenia: Current Findings and Research Perspectives. Popovic D, Schmitt A, Kaurani L, Senner F, Papiol S, Malchow B, Fischer A, Schulze TG, Koutsouleris N, Falkai P. Front Neurosci (2019)
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Innate immune memory in the brain shapes neurological disease hallmarks. Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ. Nature (2018)
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The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. Martinez Hernandez A, Urbanke H, Gillman AL, Lee J, Ryazanov S, Agbemenyah HY, Benito E, Jain G, Kaurani L, Grigorian G, Leonov A, Rezaei-Ghaleh N, Wilken P, Arce FT, Wagner J, Fuhrmann M, Caruana M, Camilleri A, Vassallo N, Zweckstetter M, Benz R, Giese A, Schneider A, Korte M, Lal R, Griesinger C, Eichele G, Fischer A. EMBO Mol Med. (2018)
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KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Cell Rep. (2017)
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HDAC1 links early life stress to schizophrenia-like phenotypes Bahari-Javan S, Varbanov H, Halder R, Benito E, Kaurani L, Burkhardt S, Anderson-Schmidt H, Anghelescu I, Budde M, Stilling RM, Costa J, Medina J, Dietrich DE, Figge C, Folkerts H, Gade K, Heilbronner U, Koller M, Konrad C, Nussbeck SY, Scherk H, Spitzer C, Stierl S, Stöckel J, Thiel A, von Hagen M, Zimmermann J, Zitzelsberger A, Schulz S, Schmitt A, Delalle I, Falkai P, Schulze TG, Dityatev A, Sananbenesi F, Fischer A. Proc Natl Acad Sci U S A. (2017)
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TBK1 duplication is found in normal tension and not in high tension glaucoma patients of Indian origin. Kaurani L, Vishal M, Ray J, Sen A, Ray K, Mukhopadhyay A. J Genet. (2016)
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Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma Vishal M, Sharma A, Kaurani L, Alfano G, Mookherjee S, Narta K, Agrawal J, Bhattacharya I, Roychoudhury S, Ray J, Waseem NH, Bhattacharya SS, Basu A, Sen A, Ray K, Mukhopadhyay A. BMC Med Genomics. (2016)
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Evaluation of genetic association of the INK4 locus with primary open angle glaucoma in East Indian population Vishal M, Sharma A, Kaurani L, Chakraborty S, Ray J, Sen A, Mukhopadhyay A. Ray K. Sci Rep. (2014)
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Gene-rich large deletions are overrepresented in POAG patients of Indian and Caucasian origins Kaurani L, Vishal M, Kumar D, Sharma A, Mehani B, Sharma C, Chakraborty S, Jha P, Ray J, Sen A, Dash D, Ray K, Mukhopadhyay A. Invest Ophthalmol Vis Sci. (2014)